We evaluated the utility of procalcitonin to improve the accuracy of clinical and microbiological parameters in diagnosing ventilation-associated pneumonia (VAP). Sequential measurement of procalcitonin and C-reactive protein, and the calculation of the simplified Clinical Pulmonary Infection
نویسندگان
چکیده
Paula Ramirez , Miguel Angel Garcia , Miquel Ferrer , Jesus Aznar , Mauricio Valencia , Jose Miguel Sauquillo , Rosario Menendez , Miguel Angel Asenjo 6 Antoni Torres . ! 1 Unidad de Cuidados Intensivos, 2 Departamentos de Biopatologia, 3 Microbiologia, and 4 Neumologia, Hospital Universitario La Fe, Valencia; 5 Unidad de Cuidados Intensivos, Hospital de Sagunto, Sagunto, Valencia; 6 Unitat dAvaluacio, Suport i Prevencio and 7 Unidad de Cuidados Intensivos e Intermedios Respiratorios, Servei de Pneumologia, Institut Clinic del Torax, Hospital Clinic, Institut dInvestigacions Biomediques August Pi I Sunyer (IDIBAPS), Barcelona, Spain. ! Dr. Valencia is a research fellow in Hospital Clínic, Barcelona, from Universidad Pontificia Bolivariana de Medellín, Colombia, supported by Fondo de Investigaciones Sanitarias Fellowship. ! Supported by CibeRes (ISCiii-CB06/06/0028), 2005 SGR 00822, ERS Fellowship, and IDIBAPS. ! Corresponding author: Antoni Torres, MD. Servei de Pneumologia, Institut Clínic del Tòrax, Hospital Clinic, Villarroel, 170. E-08036 Barcelona, Spain. Phone/Fax: + 34 93 227 55 49. E-mail: [email protected] Running title: Procalcitonin in diagnosis of VAP Word count of the body of the manuscript: 2,602
منابع مشابه
Sequential measurements of procalcitonin levels in diagnosing ventilator-associated pneumonia.
The utility of procalcitonin levels to improve the accuracy of clinical and microbiological parameters in diagnosing ventilator-associated pneumonia (VAP) was evaluated. Sequential measurement of procalcitonin and C-reactive protein levels and the calculation of the simplified Clinical Pulmonary Infection Scores (CPIS) were performed in 44 patients mechanically-ventilated for >48 h with neither...
متن کاملEffect of vitamin D supplementation on procalcitonin as prognostic biomarker in patients with ventilator associated pneumonia complicated with vitamin D deficiency
Ventilator-associated pneumonia (VAP) is a common and serious problem that develops after more than 48 hours of mechanical ventilation. Improving the activity of immune system with vitamin D, and its consequent impact on prognostic biomarkers of VAP was studied in the current study. A randomized double blind placebo controlled clinical trial was designed. A total of 46 patients with VAP, who w...
متن کاملEffect of vitamin D supplementation on procalcitonin as prognostic biomarker in patients with ventilator associated pneumonia complicated with vitamin D deficiency
Ventilator-associated pneumonia (VAP) is a common and serious problem that develops after more than 48 hours of mechanical ventilation. Improving the activity of immune system with vitamin D, and its consequent impact on prognostic biomarkers of VAP was studied in the current study. A randomized double blind placebo controlled clinical trial was designed. A total of 46 patients with VAP, who w...
متن کاملProcalcitonin: A Reliable Marker for the Diagnosis of Neonatal Sepsis
Objective(s) In the last few years, serum procalcitonin has been proposed as an early marker of infections in neonates, with varying results. In this study, we aimed to investigate the value of procalcitonin, and C- reactive protein in establishing the diagnosis of neonatal sepsis. Materials and Methods Blood samples were collected at admission from 69 neonates with suspected infection (admi...
متن کاملعنوان: Impact of Care Program on Ventilator-Associated Pneumonia Incidence: A Clinical Trial
چکیده: Background: Ventilator-associated pneumonia (VAP) is one of the common problems in patients who are under mechanical ventilation and increases the hospitalization duration and treatment expenses. The current study was conducted to determine the impact of a care program on VAP. Methods: This clinical trial was performed on intubated patients who were under mechanical ventilation in Intens...
متن کامل